What is tricresyl phosphate used for?

Tricresyl Phosphate is a colorless, odorless liquid that is a mixture of three different isomers. It is used as an additive in lubricating oils and a plasticizer, and as a fire retardant.

What are the harmful effects of tri ortho cresyl phosphate?

It is a toxic substance that causes neuropathy, paralysis in the hands and feet, and/or death for humans and animals alike. It can be ingested, inhaled, or even absorbed through the skin. Its ortho-isomer is notoriously known as a source of several delayed neurotoxic outbreaks across recent history.

Is Phosphate toxic to humans?

Phosphate excess has been well recognized as a critical factor in the pathogenesis of mineral and bone disorders associated with chronic kidney disease, but recent investigations have also uncovered toxic effects of phosphate on the cardiovascular system and the aging process.

What is TOCP oil?

Tricresyl phosphate (TCP) is widely used in lacquers and varnishes, as a plasticizer in vinyl plastics, and as an additive in lubricating oils (1). TCP usually exists along with its iso- meric forms, viz., ortho, meta, and para, of which tri-o-cresyl phosphate (TOCP) is a highly toxic and cumulative poison (1, 2).

What is tri ortho cresyl phosphate?

Triorthocresyl phosphate (TOCP) is an organophosphorus substance that has been responsible for several incidents of mass poisoning. During prohibition, contamination of an alcoholic beverage containing ginger extract with TOCP led to an epidemic that became known as the Ginger-Jake syndrome.

Is TCP edible?

Published advice states that TCP should not be swallowed, and recommends drinking plenty of water if 30ml or more of TCP is swallowed, and seeking medical advice if discomfort persists.

Is phosphate Good or bad?

High-normal levels of phosphate in the blood are linked to a higher risk of cardiovascular disease, calcium deposits and hardening of the arteries in the heart, even in healthy young men. In the Framingham Offspring Study, high-normal phosphate blood levels were found to be a predictor of heart attacks.

How does phosphate affect the body?

Phosphate is necessary for the formation of bone and teeth. Phosphate is also used as a building block for several important substances, including those used by the cell for energy, cell membranes, and DNA (deoxyribonucleic acid). The body obtains phosphate from foods and excretes it in urine and sometimes stool.

What is the full form of TOCP?

3.2 Triorthocresyl Phosphate. Triorthocresyl phosphate (TOCP) is an organophosphorus substance that has been responsible for several incidents of mass poisoning.

Can I use TCP as a mouthwash?

The instructions on the TCP bottle state that TCP can be used for sore throats, mouth ulcers, cuts, grazes, bites and stings, boils, spots and pimples. It can also be used as a mouthwash when diluted, and can also be used as a general disinfectant.

What are benefits of phosphate?

It plays an important role in how the body uses carbohydrates and fats. It is also needed for the body to make protein for the growth, maintenance, and repair of cells and tissues. Phosphorus also helps the body make ATP, a molecule the body uses to store energy. Phosphorus works with the B vitamins.

What happens if your phosphate levels are low?

Symptoms of hypophosphatemia occur only when the phosphate level in blood becomes very low. Muscle weakness develops, followed by stupor, coma, and death. In mild chronic hypophosphatemia, the bones can weaken, resulting in bone pain and fractures. People may become weak and lose their appetite.

What causes phosphate deficiency?

Long-term starvation, malnutrition, and anorexia can deplete the body’s stores of phosphorous over time. Acute hypophosphatemia is especially common in hospital patients undergoing refeeding. Additional causes include chronic infections, Crohn’s disease, or malignant tumors. Hyperparathyroidism.

What is Cotp?

Captain of the Port (COTP) means the Coast Guard officer designated by the Commandant to command a COTP Zone as described in part 3 of this chapter.

Which is stronger Dettol or Savlon?

Savlon was proved effective antiseptic than dettol and they positioned their brand as An antiseptic that doesn’t hurts while healing wounds and has a better smell.

Can you rinse your mouth with TCP?

Uses. The instructions on the TCP bottle state that TCP can be used for sore throats, mouth ulcers, cuts, grazes, bites and stings, boils, spots and pimples. It can also be used as a mouthwash when diluted, and can also be used as a general disinfectant.

What are symptoms of phosphorus deficiency?

Symptoms appearing with a phosphorus deficiency:

• Poor appetite.
• Anemia.
• Muscle weakness.
• Bone pain.
• Bone disease (osteomalacia, rickets)
• Confusion.
• Increased susceptibility to infections.