What is the brand name for nelfinavir?

Nelfinavir, sold under the brand name Viracept, is an antiretroviral medication used in the treatment of HIV/AIDS. Nelfinavir belongs to the class of drugs known as protease inhibitors (PIs) and like other PIs is almost always used in combination with other antiretroviral drugs.

What is nelfinavir used for?

Nelfinavir is used along with other medications to treat human immunodeficiency virus (HIV) infection. Nelfinavir is in a class of medications called protease inhibitors. It works by decreasing the amount of HIV in the blood.

What should nelfinavir be mixed with?

Take this medicine with food. Measure the dose of the powder using the scoop provided. In a separate container, mix with a small amount of water, milk, formula, soy formula, soy milk, dietary supplements, or dairy foods like pudding or ice cream.

What type of inhibitor is nelfinavir?

Conclusions: Nelfinavir is a lead HIV protease inhibitor with pleiotropic effects in cancer cells. Given its wide spectrum of activity, oral availability, and familiarity of administration, nelfinavir is a Food and Drug Administration–approved drug that could be repositioned as a cancer therapeutic.

What is the mechanism of action of nelfinavir?

Nelfinavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.

What is the brand name of saquinavir?

Saquinavir (brand name: Invirase) is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in people over 16 years of age. Saquinavir is always used in combination with the HIV medicine ritonavir (brand name: Norvir) and other HIV medicines.

What is the structure of nelfinavir?

C32H45N3O4SNelfinavir / Formula

What is the mechanism of saquinavir?

Saquinavir is a peptide-like substrate analogue that binds to the protease active site and inhibits the activity of the enzyme. Saquinavir inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature noninfectious virus particles.

What type of inhibitor is saquinavir?

Saquinavir is an HIV protease inhibitor with no, or limited, effect on the activity of other structurally related human aspartic proteinases.

How do you administer saquinavir?

Saquinavir comes as a capsule and a tablet to take by mouth. It is usually taken at the same time as ritonavir (Norvir) two times a day within 2 hours after a full meal. It may be easier to remember to take saquinavir if you take it with meals. Take saquinavir at around the same times every day.

Is saquinavir still used?

Saquinavir was approved for use in the United States in 1995 and is still widely used in combination with other antiretroviral agents for the prevention and treatment of HIV infection in adults and children. Saquinavir is available under the brand name Invirase in 200 mg capsules and 500 mg tablets.

What drug must be taken with saquinavir?

Saquinavir belongs to a class of drugs known as protease inhibitors. It must be given with ritonavir, another protease inhibitor, to increase (“boost”) the levels of saquinavir.