What type of tumor is pheochromocytoma?

Pheochromocytoma is a type of neuroendocrine tumor that grows from cells called chromaffin cells. These cells produce hormones needed for the body and are found in the adrenal glands. The adrenal glands are small organs located in the upper region of the abdomen on top of the kidneys.

What are the differential diagnosis for pheochromocytoma?

Pheochromocytoma must be differentiated from other causes of paroxysmal hypertension including severe paroxysmal hypertension (pseudopheochromocytoma), panic disorder, factitious hypertension, carcinoid syndrome, migraine headache, hyperthyroidism, renovascular hypertension, hypoglycemia, labile hypertension (White …

What is the difference between paraganglioma and pheochromocytoma?

Pheochromocytoma and paraganglioma are rare tumors that come from the same type of tissue. Pheochromocytoma is a rare tumor that forms in the adrenal medulla (the center of the adrenal gland). Paragangliomas form outside the adrenal gland.

Why is pheochromocytoma known as 10% tumor?

They are often called the “10% tumor” because it was commonly thought that 10% of pheochromocytomas are: Malignant – 10% behave like cancer and can spread. Bilateral – 10% are found in both adrenal glands.

What are the signs and symptoms associated with pheochromocytoma?

Signs and symptoms of pheochromocytomas often include:

• High blood pressure.
• Headache.
• Heavy sweating.
• Rapid heartbeat.
• Tremors.
• Pallor.
• Shortness of breath.
• Panic attack-type symptoms.

What can mimic a pheochromocytoma?

Various tumors including neuroblastomas, ganglioneuroblastomas and ganglioneuromas may mimic pheochromocytomas/paragangliomas.

Can a CT scan detect pheochromocytoma?

Computed tomography (CT) CT scans can reveal adrenal pheochromocytomas larger than 5–10 mm with sensitivity >95% (34).

What is the classic triad of pheochromocytoma?

Pheochromocytoma classically presents with paroxysms of hypertension and adrenergic symptoms including classic triad of episodic headache, sweating, and tachycardia.

How do you confirm pheochromocytoma?

Because catecholamine relase varies throughout the day, the best method of diagnosing pheochromocytomas is using a 24-hour urine collection. This involves obtaining a special urine container, which has a small amount of preservative, from a medical laboratory and filling it with one entire day’s worth of urine.

Can pheochromocytoma be misdiagnosed?

Conclusion The clinical appearance of pheochromocytoma is complicated and lacking in specificity, together with the tumor secretes a great deal of catecholamine which result in abnormality of blood glucose, blood lipid and abnormal hormone secretion, so pheochromocytoma is easily diagnosed mistakenly.

What is the classic clinical triad of pheochromocytoma?

What is the pathophysiology of glomus tumors caused by radiology?

Radiographs glomus tumors can produce a pressure erosion of the underlying bone and an associated deformity of the bone cortex.

What is pheochromocytoma plus ganglioneuroma?

Distinct from composite pheochromocytoma, which are tumors composed of pheochromocytoma plus ganglioneuroma, ganglioneuroblastoma, neuroblastoma or peripheral nerve sheath tumors

What are glomus tumors with prominent hemangiopericytic vasculature?

Glomangiopericytoma may be used for glomus tumors with prominent hemangiopericytic vasculature; however, these tumors are different from the pericytic site specific sinonasal glomangiopericytoma

Which lab tests are used in the workup of pheochromocytoma?

E. Synaptophysin, chromogranin, S100. The clinical presentation and image are diagnostic of a pheochromocytoma. Synaptophysin, chromogranin and S100 are positive in pheochromocytoma.AE1/AE3, CK7 and TTF1 are consistent with metastatic lung adenocarcinoma.