What is NA12878?

In 2015, NIST released the pilot genome Reference Material 8398, which is genomic DNA (NA12878) derived from a large batch of the Coriell cell line GM12878, characterized for high-confidence SNPs, indel, and homozygous reference regions (Zook, et al., Nature Biotechnology 2014 and Zook, et al., Nature Biotechnology …

What is GIAB?

The Genome in a Bottle Consortium (GIAB) is a public-private-academic consortium hosted by the National Institute of Standards and Technology (NIST) to develop the technical infrastructure (reference standards, reference methods, and reference data) to enable translation of whole human genome sequencing to clinical …

What is GM12878?

GM12878 is a lymphoblastoid cell line produced from the blood of a female donor with northern and western European ancestry by EBV transformation. It was one of the original HapMap cell lines and has been selected by the International HapMap Project for deep sequencing using the Solexa/Illumina platform.

What is nanopore technology used for?

Nanopore sequencing is used to determine the sequence of DNA/RNA bases. You can think of this like trying to complete two jigsaws of the same photograph — one with significantly larger pieces than the other.

What is HapMap project?

International HapMap Project, an international collaboration aimed at the identification of genetic variations contributing to human disease through the development of a haplotype (haploid genotype) map of the human genome.

What is H1 cell line?

“H1 is one of the most extensively studied and characterized stem cell lines among researchers worldwide and, along with other early Thomson lines, is considered the ‘gold standard’ for stem cell research by many scientists,” stated Erik Forsberg, WiCell executive director.

What are HeLa S3 cells?

HeLa S3 cells are a clonal derivative of the parent HeLa cell line (ATCC CCL-2). The HeLa S3 clone has been very useful in the clonal analysis of mammalian cell populations relating to chromosomal variation, cell nutrition, and plaque-forming ability.

Who invented nanopore?

David Deamer
The concept of nanopore sequencing was envisioned in the early 1990s by David Deamer (UC Santa Cruz) and Daniel Branton (Harvard).

Who owns Oxford Nanopore?

Oxford Nanopore Technologies

Industry	Nanopore sequencing
Founder	Hagan Bayley Gordon Sanghera Spike Willcocks
Headquarters	Oxford Science Park, Oxford , United Kingdom
Key people	Hagan Bayley Clive G. Brown (CTO) Jim McDonald (CFO) John Milton (CSO) Gordon Sanghera (CEO) Spike Willcocks (VP)
Website	nanoporetech.com

Who owns the HapMap?

The International HapMap Project is a partnership of scientists and funding agencies from Canada, China, Japan, Nigeria, the United Kingdom and the United States.

What are benefits of HapMap?

The HapMap will allow the discovery of sequence variants that affect common disease, will facilitate development of diagnostic tools, and will enhance our ability to choose targets for therapeutic intervention.

What is H9 cell line?

This human ES cell line expresses cell surface markers specific to undifferentiated nonhuman primate ES and human EC cells: stage-specific embryonic antigen (SSEA)–3, SSEA-4, TRA-l-60, TRA-1- 81, and alkaline phosphatase. It has a normal 46, XX karyotype. Teratomas are formed upon cell injection into SCID mice.

What is H9 cells?

The H9 clone was selected for permissiveness for HIV-1 replication, and has been used to isolate and propagate HIV-1 from the blood of patients with acquired immunodeficiency syndrome (AIDS) and pre-AIDS conditions. Karyotype. This is a near triploid cell line (modal number = 69; range = 58 to 74).

What media is used for HeLa cells?

Mammalian Cell Lines

Cell Line	Cell Type	Medium*
HeLa	epithelial	MEM and 10% FBS plus NEAA (in suspension, S-MEM)
HEp-2	epithelial	MEM and 10% FBS
HL-60	lymphoblast	RPMI-1640 and 20% FBS
HT-1080	epithelial	MEM and 10% HI FBS plus NEAA

What is A549 cells?

A549 cells are lung carcinoma epithelial cells that constitute a cell line. A549 is one of the commonly used cell lines for a wide range of research applications.

Is Oxford Nanopore a biotech company?

This Biotech Company Finds DNA Testing Is the Right Formula for Growth. Biotech company Oxford Nanopore Technologies, which listed on the London market eight months ago, produces Covid-19 technology to identify new variants, but its expertise in testing DNA and analyzing data is where its growth lays.

How much does nanopore cost?

Nanopore DNA sequencing devices MinION Starter Packs are available from just $1,000 providing low-cost access to the benefits of long-read, real-time DNA sequencing.

Can I buy Oxford Nanopore stock?

You can: Invest in and own Oxford Nanopore shares through share dealing. Trade on upward and downward share price movements with spread bets or CFDs.

What is HapMap used for?

The haplotype map, or “HapMap,” is a tool that allows researchers to find genes and genetic variations that affect health and disease. The DNA sequence of any two people is 99.5 percent identical. The variations, however, may greatly affect an individual’s disease risk.

What are the benefits of the HapMap?