What is MV4 11 cell line?

MV4-11 is a human AML cell line established from blasts cells of 10 years old male with biphenotypic B-myelomonocytic leukemia (AML FAB M5) that carry translocation t(4;11) and a FLT3-ITD mutation.

What is MOLM 13 cell line?

MOLM-13 and MOLM-14 are the first cell lines with, and represent the third reported case of, MLL gene rearrangement arising via chromosomal insertion.

What is RT4 cell line?

RT4 is a cell line exhibiting epithelial morphology that was isolated from urinary bladder tissue derived from a 63-year-old, White, male patient with transitional cell papilloma. Use these cells in your immuno-oncology research. Homo sapiens, human. Morphology epithelial Tissue Urinary bladder Disease.

How do you identify a cell line?

Cell lines can be tested and identified using multiallelic variable number of tandem repeats (VNTR). HLA typing and DNA fingerprinting using short tandem repeat (STR) and a variable number of tandem repeats for intra-species cross-contamination have been used for cell line identification.

What is Jurkat cell line?

Jurkat cells are an immortalized line of T lymphocyte cells. And they are used to study acute T cell leukemia, T cell signaling, and the expression of a number of chemokine receptors susceptible to viral entry, particularly HIV. Jurkat cells are also useful in science due to their ability to produce interleukin 2.

What is acute Biphenotypic leukemia?

Biphenotypic acute leukaemia (BAL) is an uncommon type of leukemia which arises in multipotent progenitor cells which have the ability to differentiate into both myeloid and lymphoid lineages. It is a subtype of “leukemia of ambiguous lineage”.

What is Nalm6?

Nalm6 is a B cell precursor leukemia cell line initiated from an adolescent male. It is a CD24-positive xenograft model of acute lymphoblastic leukemia.

What is transitional cell papilloma?

Transitional cell papilloma is a benign tumour of the bladder of epithelial origin [1]. It is very rare, and is composed of normal exophytic urothelium arranged on a delicate fibrovascular stalk [2].

What is normal cell line?

C28/I2 Human Chondrocyte Cell Line is widely used as a model cell line for studying normal and pathological cartilage repair mechanisms related to chondrocyte biology and physiology.

What is cell line example?

HeLa cells are an example of an immortal cell line. These are human epithelial cells obtained from fatal cervical carcinoma transformed by human papilloma virus 18 (HPV18). Indefinite cell lines are easy to manipulate and maintain. However these cell lines have a tendency to change over a period of time.

Is Jurkat CD4 or CD8?

CD4+
Jurkat is a CD4+/CD8- T-cell lymphoma that expresses an endogenous TCR. The T2 line is a TAP-deficient T-cell/B-cell hybridoma expressing HLA-A2.

What is the HLA type of Jurkat cells?

The Jurkat HLA panel is comprised of eleven (11) genetically modified cell lines targeting MHC Class I HLA molecules in a Jurkat T lymphocyte parental cell line background. The full HLA panel consists of a Beta-2 microglobulin (β2M) knockout cell line and an additional ten (10) monoallelic HLA expression cell lines.

What does Biphenotypic mean?

Biphenotypic acute leukaemia (BAL) is a mixture of both types of acute leukaemias, acute myeloid leukaemia (AML) and acute lymphoblastic leukaemia (ALL). Biphenotypic (bye-fee-no-tip-ik) just means ‘both types’. There are several tests that help to determine each type of leukaemia.

What causes acute Biphenotypic leukemia?

About 5% of acute leukaemia cases are BAL. BAL can occur in all ages of people but occurs more in adults than in children….Biphenotypic acute leukaemia.

Biphenotypic acute leukemia
Symptoms	Lymphadenopathy, anemia
Causes	virus, hereditary
Diagnostic method	Bone marrow examination
Treatment	Chemotherapy, stem cell therapy

What are Raji cells?

Raji cells are a human B lymphoblastoid cell line originally derived from a patient with Burkitt lymphoma.

Is transitional cell papilloma malignant?

Papillary urothelial hyperplasia shares a benign, normal-appearing cytology of the proliferating urothelium in common with urothelial papillomas, but, given the hyperplastic urothelium, is probably a closer mimic of papillary urothelial neoplasms of low malignant potential/Grade I transitional cell carcinoma.

Is papilloma a benign tumor?

Intraductal papillomas are benign (non-cancerous), wart-like tumors that grow within the milk ducts of the breast. They are made up of gland tissue along with fibrous tissue and blood vessels (called fibrovascular tissue).

How can you tell if a cell is cancerous?

Typically, the nucleus of a cancer cell is larger and darker than that of a normal cell and its size can vary greatly. Another feature of the nucleus of a cancer cell is that after being stained with certain dyes, it looks darker when seen under a microscope.

What is a tumor cell line?

(KAN-ser sel line) Cancer cells that keep dividing and growing over time, under certain conditions in a laboratory. Cancer cell lines are used in research to study the biology of cancer and to test cancer treatments.

What are types of cell line?

Attached cell lines can be classified as 1) endothelial such as BAE-1, 2) epithelial such as HeLa, 3) neuronal such as SH-SY5Y, or 4) fibroblast such as MRC-5.