What is eraxis used for?

Eraxis (anidulafungin) is an antifungal antibiotic that treats candida (yeast) infections in the blood, or in the stomach or esophagus.

What class of drug is anidulafungin?

Anidulafungin belongs to a class of drugs known as echinocandins. It works by stopping the growth of fungi.

What drugs are Echinocandins?

The introduction of echinocandins, a new class of antifungals, against this backdrop, is a promising development in antifungal therapy. Echinocandins are a group of semisynthetic, cyclic lipopeptides with an N-linked acyl lipid side chain. The drugs in the class are: caspofungin, micafungin and anidulafungin.

What is anidulafungin used for?

It is used to treat fungal infections including candidemia (fungal infection in the blood), candida peritonitis and abscess (fungal infection in the stomach), esophageal candidiasis (fungal infection in the esophagus), and other fungal infections (including infections in the stomach).

How much does eraxis cost?

The cost for Eraxis intravenous powder for injection 50 mg is around $110 for a supply of 1 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. Eraxis is available as a brand name drug only, a generic version is not yet available.

How long does anidulafungin take to work?

Anidulafungin is sometimes given for up to 7 days after your symptoms clear up, or up to 14 days after lab tests show that the infection has cleared.

Is echinocandins a fungicide?

The major advantage of echinocandins relative to other antifungal agents is their fungicidal activity against Candida spp, including fluconazole-resistant C. glabrata and C.

What are the side effects of echinocandins?

Side effects of echinocandin antifungals may include:

• Facial flushing (temporary reddening of the skin because of dilation of blood vessels beneath the skin)
• Severe rash.
• Itching.
• Fever.
• Thrombophlebitis (inflammation of a vein, usually in the leg)
• Hepatitis (inflammation of the liver)

How do you administer anidulafungin?

The recommended dose is a single 100 mg loading dose of ERAXIS on Day 1, followed by 50 mg daily dose thereafter. Patients should be treated for a minimum of 14 days and for at least 7 days following resolution of symptoms. Duration of treatment should be based on the patient’s clinical response.

How do you administer eraxis?

The recommended dose is a single 100 mg loading dose of ERAXIS on Day 1, followed by a 50 mg once daily maintenance dose thereafter. Patients should be treated for a minimum of 14 days and for at least 7 days following resolution of symptoms. Duration of treatment should be based on the patient’s clinical response.

Is itraconazole safe to take?

Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: numbness/tingling of arms/legs, hearing loss, mental/mood changes (such as depression). Itraconazole has rarely caused very serious (possibly fatal) liver disease.

Does anidulafungin cover Aspergillus?

Anidulafungin is a new echinocandin that has been introduced for use in patients with Candida and Aspergillus infections.

When do you use echinocandins?

Echinocandins are widely used for the treatment of invasive candidiasis, especially in critically ill and neutropenic patients [4]. They are also used for empiric antifungal therapy in patients with neutropenic fever.

How do echinocandins work to fight off fungal infections?

The echinocandins are a new class of antifungals, developed in response to the need for safe and effective antifungals for the treatment of invasive fungal infections. These agents work by inhibiting 1,3-beta-d-glucan synthase, an enzyme essential for production of cell walls in select fungi.

Can ERAXIS be refrigerated?

ERAXIS unreconstituted vials should be stored in a refrigerator at 2°C – 8°C (36°F – 46°F). Do not freeze.

Qual o prazo de validade do medicamento ecalta?

Do ponto de vista microbiológico, Ecalta ® deve ser utilizado imediatamente. Número de lote e datas de fabricação e validade: vide embalagem. Não use medicamento com o prazo de validade vencido.

Quais são as contraindicações do ecalta?

Quais as contraindicações do Ecalta? Ecalta ® é contraindicado a pacientes com hipersensibilidade (alergia) a anidulafungina, a outras equinocandinas (classe de antifúngicos) (por exemplo, a caspofungina) ou a qualquer outro componente da fórmula. Como usar o Ecalta?

Qual é o prazo de validade da solução para infusão de ecalta?

A estabilidade química e física “em uso” da solução para infusão de Ecalta foi demonstrada por 24 horas a 5°C. Do ponto de vista microbiológico, Ecalta deve ser utilizado imediatamente. O prazo de validade está indicado na embalagem externa do produto. TODO MEDICAMENTO DEVE SER MANTIDO FORA DO ALCANCE DAS CRIANÇAS.