What does low pneumococcal antibodies mean?

Low Baseline Pneumococcal Antibody Titers Predict Specific Antibody Deficiency, Increased Upper Respiratory Infections, and Allergy Sensitization. Allergy Rhinol (Providence).

What are normal range for pneumococcal antibodies?

The geometrical mean titre of pneumococcal IgG levels was determined from a healthy UK adult population by the current clinical assay [10] with a level of >640 µg/ml being regarded as ‘normal’ and ≥50 µg/ml being regarded as positive.

What is pneumococcal AB blood test?

This test measures IgG antibody levels to Streptococcus Pneumoniae to determine how well a person has responded to vaccination. Streptococcus Pneumoniae (pneumococcal) is a bacteria that is responsible for the majority of cases of pneumonia as well as other conditions including bronchitis, septicemia, and meningitis.

What is considered a protective pneumococcal antibody level?

Pneumococcal titer levels ≥0.2 µg/mL were considered as protective against invasive pneumococcal disease, and levels ≥1.3 µg/mL were considered protective against noninvasive pneumococcal disease.

What are the 23 serotypes?

PNEUMOVAX 23 is a vaccine indicated for active immunization for the prevention of pneumococcal disease caused by the 23 serotypes contained in the vaccine (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, and 33F).

Can low immunoglobulin cause fatigue?

Fatigue Is Common in Immunoglobulin G Subclass Deficiency and Correlates With Inflammatory Response and Need for Immunoglobulin Replacement Therapy. Purpose: Individuals with immunoglobulin G deficiency (IgGsd) often complain of fatigue. The correlation between systemic inflammation and fatigue is unknown.

How many serotypes of Streptococcus pneumoniae are there?

There are more than 100 distinct serotypes of Streptococcus pneumoniae. The pneumococcal capsule serves as the target for current highly effective multivalent vaccines against this global pathogen.

How do you get pneumococcal disease?

Pneumococcal disease is spread from person to person through coughing, sneezing, and close contact. Some people, especially children, can carry the bacteria in their nose and throat without being sick and can spread the bacteria to others.

What does a high M pneumoniae IgG ABS mean?

What does it mean if your Mycoplasma pneumoniae IgG Abs result is too high? A positive result indicates prior exposure to Mycoplasma. A single positive IgG result may be present in the absence of any clinical symptoms as specific IgG antibodies may remain elevated long after initial infection.

What are the 23 types of pneumococcal bacteria?

PPSV23 is composed of purified preparations of pneumococcal capsular polysaccharide from 23 types of pneumococci. The serotypes are: 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F.

What is the difference between PCV13 and PPSV23?

PCV13 (pneumococcal conjugate vaccine) protects against 13 of the approximately 90 types of pneumococcal bacteria that can cause pneumococcal disease, including pneumonia, meningitis, and bacteremia. PPSV23 (pneumococcal polysaccharide vaccine) protects against 23 types of pneumococcal bacteria.

What autoimmune diseases cause low IgG?

Various autoimmune diseases are associated with IgA deficiency, including rheumatoid arthritis, systemic lupus erythematosus, Graves disease, type 1 diabetes, celiac disease, myasthenia gravis, pernicious anemia, and immune thrombocytopenic purpura.

What are pneumococcal serotypes?

The serotypes are: 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F. PPSV23 is administered by either intramuscular or subcutaneous injection. Each dose of PPSV23 contains phenol as a preservative.

What is the mean of serotype?

Definition of serotype : a group of intimately related microorganisms distinguished by a common set of antigens also : the set of antigens characteristic of such a group.

How serious is pneumococcal disease?

Invasive pneumococcal disease is a life-threatening condition that is fatal in 10 percent of cases. Older people and those with underlying medical conditions have a higher risk than others of serious complications.

What is the difference between pneumonia and pneumococcal?

Pneumonia can be classified into bacterial, viral, fungal or aspiration as the cause. Pneumococcal pneumonia specifically refers to a pneumonia caused by the Strep pneumo bacteria,” Dr. Jenkins says.

How do I read Mycoplasma test results?

Mycoplasma pneumoniae is a small bacterium transmitted via organism-containing droplets….Mycoplasma pneumoniae IgG Abs.

IgG Result	IgM Result	Interpretation
Positive	Reactive	Prior exposure to M pneumoniae detected. Confirmatory testing for IgM to M pneumonia will be performed by an immunofluorescence assay.
Equivocal

How serious is Mycoplasma pneumoniae?

Lung infections caused by M. pneumoniae are sometimes referred to as “walking pneumonia” since symptoms are generally mild. Sometimes M. pneumoniae can cause more serious lung infections that require care in a hospital though.