What causes Kaposiform Hemangioendothelioma?

Kaposiform hemangioendothelioma (KHE) may look like a birthmark, but is actually a rare benign tumor caused by the abnormal growth of blood vessels.

What is Kaposiform Hemangioendothelioma?

Kaposiform hemangioendothelioma, or KHE, is a type of tumor that grows in the blood vessels. Blood vessels help move blood around the body. This tumor usually grows just underneath the skin, but it can also grow deeper inside the chest or abdomen.

What is Kasabach-Merritt syndrome?

Kasabach-Merritt phenomenon (KMP) is a rare, potentially life-threatening condition. It occurs when certain fast-growing vascular tumors [kaposiform hemangioendothelioma (KHE) or tufted angioma (TA)] trap and destroy platelets, interfering with blood clotting and raising the risk of serious bleeding.

Is Kaposiform Hemangioendothelioma malignant?

Kaposiform Hemangioendothelioma (KHE) is a rare vascular tumor of intermediate malignant potential which shows locally aggressive growth but only rarely metastasizes. It is mostly considered to be a tumor of pediatric population but its occurrence in the adults is not uncommon as once considered.

What is Hemangioendothelioma?

Epithelioid hemangioendothelioma, or EHE, is a rare cancer that grows from the cells that make up the blood vessels. This cancer can occur anywhere in the body with the most common sites being the liver, lungs, and bone.

What causes congenital hemangioma?

A congenital hemangioma (hee-man-jee-OH-muh) is a type of birthmark that happens when a tangled group of blood vessels grow in or under a baby’s skin. Congenital means present at birth, so babies who have these hemangiomas are born with them.

What is Kaposiform Lymphangiomatosis?

Kaposiform lymphangiomatosis (KLA) is an extremely rare condition in which the vessels that carry lymphatic fluid throughout the body expand and interconnect. These abnormal lymphatic vessels invade and cause damage to surrounding tissue, bones and organs.

How is Kasabach-Merritt syndrome treated?

A major mainstay of the treatment of Kasabach-Merritt syndrome is surgical excision. This approach is recommended for single cutaneous lesions or multiple lesions in the spleen (splenectomy) or liver (wedge resection/hepatectomy) [2, 12, 13]. This is the only treatment that provides cure in significant number of cases.

What are the two types of hemangiomas?

The two main types of infantile hemangiomas are:

• Superficial hemangiomas, or cutaneous (“in-the-skin”) hemangiomas, grow on the skin surface.
• Deep hemangiomas grow under the skin, making it bulge, often with a blue or purple tint.

What causes Lymphangiomatosis?

The exact cause of diffuse pulmonary lymphangiomatosis is unknown. Lymphangiomatosis in general is believed to result from abnormalities in the development of the lymphatic vascular system during embryonic growth.

How is Lymphangioma treated?

Treating Lymphangioma Surgical excision is employed for the more superficial lesions, while deeper lesions are typically treated with sclerotherapy, the injection of a chemical agent that causes the lesion to shrink. This treatment is also used in the treatment of varicose veins.

Can hemangioma cause low platelets?

Kasabach–Merritt syndrome, also known as hemangioma with thrombocytopenia, is a rare disease, usually of infants, in which a vascular tumor leads to decreased platelet counts and sometimes other bleeding problems, which can be life-threatening. It is also known as hemangioma thrombocytopenia syndrome.

Can hemangiomas cause anemia?

Despite their benign biologic behavior, hemangiomas can cause severe anemia secondary to tumor-associated blood loss.

What causes hemangioma in newborns?

Infantile hemangiomas are made up of blood vessels that form incorrectly and multiply more than they should. These blood vessels receive signals to grow rapidly early in a baby’s life. Most infantile hemangioma will appear at birth or within the first few weeks after birth.

What is Kaposiform lymphangiomatosis?

What is the symptoms of lymphangiomatosis?

Diffuse pulmonary lymphangiomatosis is difficult to diagnose due to its presentation with nonspecific symptoms such as wheezing, cough, dyspnea, hemoptysis, and chest pain, and is commonly misdiagnosed as asthma or other respiratory diseases.