What are the side effects of nicorandil?

Side effects of nicorandil

• Headaches. Make sure you rest and drink plenty of fluids.
• Feeling dizzy or weak. If nicorandil makes you feel dizzy or weak, stop what you’re doing and sit or lie down until you feel better.
• Feeling or being sick (nausea or vomiting)
• Flushing.

What are the side effects of ranolazine?

Side Effects

• Bloating or swelling of the face, arms, hands, lower legs, or feet.
• chest tightness.
• difficult or labored breathing.
• fast, irregular, pounding, or racing heartbeat or pulse.
• lightheadedness.
• rapid weight gain.
• tingling of the hands or feet.
• unusual weight gain or loss.

What is side effect of diltiazem?

Common side effects include swollen hands, ankles or feet, headaches and constipation. Diltiazem starts to work on the day you start taking it, but for high blood pressure and angina it may take a couple of weeks to work fully.

What is the side effect of nitroglycerin?

Headache, dizziness, lightheadedness, nausea, flushing, and burning/tingling under the tongue may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Can nicorandil cause bradycardia?

After detailed evaluation, nicorandil was suspected to be the cause of hyperkalemia which induced bradycardia. This case reminds us that physicians should be aware of this potential complication in patients receiving ATP-sensitive potassium channel activator.

Does nicorandil affect blood pressure?

Therapeutic doses of nicorandil may lower the blood pressure of hypotensive patients.

Which of the following is a serious side effect of Ranexa?

Call your doctor at once if you have: a light-headed feeling, like you might pass out; fast or pounding heartbeats, fluttering in your chest; or. kidney problems–little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath.

Can ranolazine cause bradycardia?

Ranolazine can also cause bradycardia, as noted on its FDA package insert. A review of the 5 major ranolazine trials (MARISA [9], CARISA [10], ERICA [11], MERLIN-TIMI 36, and RAN080 [12]) observed that bradycardia is seen in less than 2% of patients.

What are the worst side effects of diltiazem?

Tell your doctor right away if you have any serious side effects, including: nausea/vomiting that doesn’t stop, fainting, new or worsening symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain), slow/irregular/pounding/fast heartbeat, mental/mood …

Who should not use diltiazem?

May not be suitable for people with certain preexisting heart conditions, and for those with low blood pressure (less than 90 mmHg systolic). Caution should be used when giving diltiazem to people with kidney or liver disease because not many studies have been done in people with these conditions.

Which of the following is the most common adverse effect of nitroglycerin?

The more common side effects of nitroglycerin can include: headache. dizziness. weakness.

What is the most serious side effect of nitroglycerin?

Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: fainting, fast/irregular/pounding heartbeat. A very serious allergic reaction to this drug is rare.

Does nicorandil increase heart rate?

Heart rate was significantly increased 30 s after administration of NTG (from 64 ± 4 to 74 ± 6 beats/min, p < 0.05) and nicorandil (from 64 ± 4 to 71 ± 3 beats/min, p < 0.01). These increases were sustained for 3 min after administration of both NTG and nicorandil.

Can nicorandil cause hypotension?

While nitrates and nicorandil are effective pharmacological agents for prevention of angina symptoms, when prescribing these drugs it is important to consider that unwanted and poorly tolerated hemodynamic side-effects such as headache and orthostatic hypotension can often occur owing to systemic vasodilatation.

What drugs should not be taken with ranolazine?

Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Amoxapine.
• Amprenavir.
• Atazanavir.
• Bepridil.
• Carbamazepine.
• Cisapride.
• Clomipramine.
• Colchicine.

Does ranolazine cause hypotension?

Additionally, ranolazine has beneficial metabolic properties and does not affect heart rate or blood pressure.

Can Ranexa cause hypotension?

Ranolazine (Ranexa) does not typically affect blood pressure like many other anti-angina medications. It can rarely cause low blood pressure.

Who should not take diltiazem?

What drugs should not be taken with diltiazem?

Other medications can affect the removal of diltiazem from your body, which may affect how this medication works. Examples include cimetidine, St. John’s wort, azole antifungals such as ketoconazole, macrolide antibiotics such as erythromycin, rifamycins including rifabutin and rifampin.

What are some signs that the patient might be getting too much diltiazem?

More common

• Body aches or pain.
• congestion.
• dryness or soreness of the throat.
• tender or swollen glands in the neck.
• trouble swallowing.

Nicorandil Tablets have an influence on the ability to drive and use machines. Indeed, as with other vasodilators, blood pressure lowering effects as well as dizziness and feeling weakness induced by nicorandil can reduce the ability to drive or to use machines.

Does nicorandil interact with acenocoumarol?

Nicorandil does not affect the pharmacodynamics of acenocoumarol. Pregnancy: There are no or limited amount of data from the use of nicorandil in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity (see section 5.3).

Is nicorandil safe for patients with diverticular disease?

Patients with diverticular disease may be at particular risk of fistula formation or bowel perforation during nicorandil treatment. Gastrointestinal perforations in context of concomitant use of nicorandil and corticosteroids have been reported. Therefore, caution is advised when concomitant use is considered.

Can nicorandil cause hyperkalaemia?

Severe hyperkalaemia has been reported very rarely with nicorandil. Nicorandil should be used with care in combination with other medical products that may increase potassium levels, especially in patients with moderate to severe renal impairment (see sections 4.5 and 4.8).