How is folotyn administered?

Folotyn® is given through a vein by intravenous (IV) injection. Folic acid and vitamin B12 supplements are also prescribed during treatment with Folotyn® to reduce the risk of possible side effects. Take as prescribed.

How much does pralatrexate cost?

The cost of Folotyn (pralatrexate injection) runs about $120,000 a year, a price tag that few drugs for incurable, rare cancers can match.

Who makes folotyn?

Allos expects to make FOLOTYN available to patients in the U.S. in October. “Individuals with peripheral T-cell lymphoma have a very poor prognosis and almost always relapse or become refractory to initial therapy. 1 As a result, there is an urgent need for new therapies to treat patients with this challenging disease.

What is folotyn used for?

Folotyn (pralatrexate injection) is an antineoplastic (anti-cancer) drug used to treat T-cell lymphoma that has spread throughout the body. Folotyn is given for relapsed T-cell lymphoma, or after other medications have been tried without successful treatment.

What are the symptoms of T-cell lymphoma?

Symptoms of T-cell lymphoma

• Swollen lymph nodes.
• Fever.
• Night sweats.
• Weight loss.
• Fatigue.
• Rash or itchy skin.
• Pain in the chest, abdomen or bones.

What class of drug is pralatrexate?

Pralatrexate injection is in a class of medications called folate analogue metabolic inhibitors. It works by killing cancer cells.

Is Pralatrexate chemotherapy?

Pralatrexate is an anti-cancer (chemotherapy) medicine that belongs to a group of medicines called antifolates used to treat patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).

Does pralatrexate cause hair loss?

The “normal” cells will grow back and be healthy but in the meantime, side effects occur. The “normal” cells most commonly affected by chemotherapy are the blood cells, the cells in the mouth, stomach and bowel, and the hair follicles; resulting in low blood counts, mouth sores, nausea, diarrhea, and/or hair loss.

How can I stop my hair falling out from methotrexate?

Supplements. People taking methotrexate or leflunomide may benefit from taking folic acid and biotin supplements. These B vitamins can help protect against hair loss. Folic acid can also help relieve some of the other side effects that can occur with methotrexate.

How will we know if the treatment is working?

After treatments like chemotherapy, radiation, immunotherapy, and targeted therapy, your doctor will examine you for any new growths. You’ll also get blood tests, X-rays, and other imaging tests. These tests will measure your tumor and see if your treatment has slowed or stopped your cancer.