How does indomethacin affect the heart?

People who take nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as indomethacin may have a higher risk of having a heart attack or a stroke than people who do not take these medications. These events may happen without warning and may cause death.

What is indomethacin used to treat?

Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate acute pain and relieve symptoms of arthritis (osteoarthritis and rheumatoid arthritis) or gout, such as inflammation, swelling, stiffness, and joint pain.

Can indomethacin cause heart palpitations?

The most serious signs of this reaction are very fast or irregular breathing, gasping for breath, or fainting. Other signs may include changes in color of the skin of the face, very fast but irregular heartbeat or pulse, hive-like swellings on the skin, and puffiness or swellings of the eyelids or around the eyes.

Can Indocin cause tachycardia?

Serious side effects of Indocin may include heart attack, stroke, skin changes (paleness, blisters, rash, and hives), weight gain, swelling, shortness of breath, tachycardia, unusual bleeding (including GI bleeding), jaundice, stomach pain, and pain with urination, bloody urine, blurry vision, and back pain.

Can indomethacin lower your heart rate?

Indomethacin raised BP and lowered pulse rates in patients taking enalapril but had little effect in patients receiving amlodipine. The difference caused by indomethacin between the two groups was 10.1/4.9 mm Hg increase in BP and a 5.6 beats/min fall in pulse in people taking enalapril.

Can indomethacin lower BP?

The most widely studied of the NSAID medications is indomethacin, which has been shown to increase mean blood pressure by as much as 5 mm Hg in treated hypertensive patients.

Does indomethacin raise blood pressure?

Does indomethacin cause anxiety?

Results: Thirty-two patients experienced a psychiatric reaction after receiving indomethacin for postpartum pain. The symptoms were often severe and included dizziness, anxiety, fear, agitation, affective lability, depersonalization, paranoia, and hallucinations.

Does indomethacin lower heart rate?

Can you take indomethacin with high blood pressure medicine?

In conclusion, the present study shows that indomethacin blunts the 24-hour antihypertensive effects of losartan and captopril. Thus, hypertensive patients receiving either captopril or losartan who require concomitant therapy with indomethacin should be monitored for alterations in blood pressure control.

Does indomethacin elevate blood pressure?

Although indomethacin increases blood pressure in certain patients, those with pre-existing hypertension are at greatest risk [5,10]. Indomethacin increases blood pressure in patients controlled on ACE inhibitors, but minimal effect is seen on patients under calcium channel blockers.

How much does indomethacin raise BP?

Will indomethacin raise blood pressure?

Can indomethacin lower your blood pressure?

Does indomethacin lower blood pressure?

What should I know about indomethacin before taking it?

Before taking this medicine. These conditions can occur without warning while you are using indomethacin, especially in older adults. You should not use indomethacin if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Can indomethacin affect my fertility?

This medicine may temporarily affect fertility (ability to have children) in women. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Indomethacin is not approved for use by anyone younger than 14 years old.

Can you take aspirin and indomethacin at the same time?

Ask a doctor or pharmacist before using any cold, allergy, or pain medicine. Many medicines available over the counter contain aspirin or other medicines similar to indomethacin. Taking certain products together can cause you to get too much of this type of medication.

What medications can cause an increase in pulse rate?

Certain medications can also temporarily affect the heart, causing an increase heart rate, such as salbutamol. Medical conditions: Certain medical conditions affect the heart, leading to rapid pulse rate.