What is the Handbook of pharmaceutical excipients?

The Handbook of Pharmaceutical Excipients is internationally recognised as the world’s most authoritative source of information on pharmaceutical excipients. It provides you with a one stop resource when researching an excipient for use.

What are excipients and why are they important?

While excipients were at one time considered to be ‘inactive’ ingredients, it is now understood that they can, in certain cases, have an impacton the safety, bioavailability and stability of the drug product as well as patient acceptability. Therefore the presence and quantity of excipients in the formulation need to be justified.

What factors should be considered when selecting excipients?

function of the excipient, the safety profile of the excipient with regard to the target age group, the exposure and the duration of use, the condition that is to be treated, patient acceptability, palatability and any known allergies and sensitisation concerns.

What are the requirements of formulation design for pediatric dosage forms?

Dosage form stability and excipient compatibility studies are also an important aspect of formulation design; however require-ments for pediatric dosage forms are largely the same as for adult preparations.

How important are excipients in the final dosage form?

Indeed, the properties of the final dosage form (i.e. its bioavailability and stability) are, for the most part, highly dependent on the excipients chosen, their concentration and interaction with both the active compound and each other. No longer can excipients be regarded simply as inert or… Expand …

How many excipient monographs are there in the DSM-5?

Over 420 fully referenced excipient monographs, many including IR, Raman, and NIR spectra 13 new monographs including several amino acids and hydrated silicon dioxide New chapters include excipient selection for orally inhaled and injectable formulations Enter voucher code PE10 at checkout.