What is the contraindication for hydrochlorothiazide?

According to the manufacturer, hydrochlorothiazide is specifically contraindicated in patients with sulfonamide hypersensitivity. Hypersensitivity reactions may occur in patients with or without a history of allergy or bronchial asthma; however, reactions are more likely to occur in patients with such history.

What are the contraindications for thiazide diuretics?

Thiazide diuretics are contraindicated for use in patients with anuria and sulfonamide allergies.

What should be monitored when taking hydrochlorothiazide?

While the drug is relatively safe, the patient’s electrolyte status has to be monitored regularly. Even though hydrochlorothiazide has been the most widely used thiazide drug for hypertension, more recent evidence indicates that it may not be as effective as some of the other thiazide diuretics.

What pregnancy category is microzide?

Pregnancy: Teratogenic Effects – Pregnancy Category B: Studies in which hydrochlorothiazide was orally administered to pregnant mice and rats during their respective periods of major organogenesis at doses up to 3000 and 1000 mg hydrochlorothiazide/kg, respectively, provided no evidence of harm to the fetus.

Is Microzide potassium sparing?

Unlike potassium sparing combination diuretic products, MICROZIDE (hydrochlorothiazide capsule) may be used in those patients in whom the development of hyperkalemia cannot be risked, including patients taking ACE inhibitors.

What pregnancy category is hydrochlorothiazide?

Hydrochlorothiazide / methyldopa Pregnancy Warnings US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Does hydrochlorothiazide dilate blood vessels?

In contrast to indapamide, hydrochlorothiazide showed a direct vascular effect (maximal vasodilation, 55±14%; P=0.013), which was inhibited by TEA (maximal vasodilation after TEA, 13±10%; P=0.02).

When should a thiazide diuretic not be used?

People who have diabetes may have increased blood sugar levels when taking thiazide diuretics. It is not recommended to use thiazide diuretics with dofetilide (Tikosyn), a drug used for treating abnormal heart rhythms, as this may increase the blood levels of dofetilide (Tikosyn) and cause abnormal heart rhythms.

What are nursing implications for hydrochlorothiazide?

Monitor signs of fluid, electrolyte, or acid-base imbalances, including dizziness, drowsiness, blurred vision, confusion, hypotension, or muscle cramps and weakness. Report excessive or prolonged symptoms to the physician.

When should I test my labs after taking hydrochlorothiazide?

MODERATE AND HIGH RISK PATIENTS (see above) – check at 4 and 10 days. Checks should also be sent after dose increases, and if diuretic doses are increased.

Is hydrochlorothiazide OK during pregnancy?

Hydrochlorothiazide may be continued during pregnancy; the use of low doses (12.5 to 25 mg daily) may minimize untoward metabolic effects, such as impaired glucose tolerance and hypokalemia. Triamterene and amiloride are not teratogenic based on small numbers of case reports.

Is moduretic safe in pregnancy?

Do not take MODURETIC if you are pregnant or intend to become pregnant unless you and your doctor have discussed the risks and benefits involved. It may affect your developing baby if you take it during pregnancy. Do not take MODURETIC if you are breast-feeding or intend to breast-feed.

Does hydrochlorothiazide deplete potassium?

Hydrochlorothiazide affects electrolyte and fluid balance in the body, which can have serious side effects. This medication may cause low sodium levels (hyponatremia), low potassium levels (hypokalemia), and low magnesium levels (hypomagnesemia).

Is hydrochlorothiazide safe during pregnancy?

Is it OK to take hydrochlorothiazide while pregnant?

Can you take hydrochlorothiazide if you’re pregnant?

The manufacturer recommends that hydrochlorothiazide should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus. The routine use of diuretics during pregnancy is not indicated or recommended.

Is hydrochlorothiazide a vasoconstrictor?

In animal and human isolated resistance arteries, hydrochlorothiazide exerts a dose-dependent direct vasodilator effect at therapeutically relevant concentrations.

Does hydrochlorothiazide cause hyperkalemia?

Hyperkalemia. Abnormal elevation of serum potassium levels (greater than or equal to 5.5 mEq/liter) can occur with all potassium-sparing diuretic combinations, including DYAZIDE (hydrochlorothiazide and triamterene).

Does hydrochlorothiazide have a black box warning?

Important warnings This drug has a black box warning. This is the most serious warning from the Food and Drug Administration (FDA).

Is hydrochlorothiazide potassium sparing?

The combination potassium-sparing diuretics are: Aldactazide (spironolactone/hydrochlorothiazide)

What are the contraindications of ultrasound?

Contraindications of Ultrasound Therapy. It should not be used when there are cancerous lesions on or near area to be treated. If a patient shows symptoms of carrying serious infectious diseases or in cases where the patient should be avoiding excess heat or fevers, it is not advised to use therapeutic ultrasound.

What are the indications of Microzide?

Indications and Usage for Microzide. Diuretics do not prevent development of toxemia of pregnancy, and there is no satisfactory evidence that they are useful in the treatment of developed toxemia. Edema during pregnancy may arise from pathological causes or from the physiologic and mechanical consequences of pregnancy.

What are the contraindications for hydrochlorothiazide?

Hydrochlorothiazide is contraindicated in patients with anuria. Hypotension, orthostatic hypotension, sympathectomy, syncope Patients with pre-existing hypovolemia or hypotension should have their condition corrected before diuretics are initiated. Orthostatic hypotension may occur during treatment with thiazide diuretics like hydrochlorothiazide.

What should I know before taking Microzide (Hydrochlorothiazide)?

Tell all of your health care providers and lab workers that you take Microzide (hydrochlorothiazide). If you are taking Microzide (hydrochlorothiazide) and have high blood pressure, talk with your doctor before using OTC products that may raise blood pressure.