What is aminophenol sulfate?

Description. 2-aminophenol sulphate belongs to the class of organic compounds known as phenylsulfates. Phenylsulfates are compounds containing a sulfuric acid group conjugated to a phenyl group. 2-aminophenol sulphate is a moderately basic compound (based on its pKa).

What is aminophenol used for?

4-Aminophenol (or para-aminophenol or p-aminophenol) is the organic compound with the formula H2NC6H4OH. Typically available as a white powder, it is commonly used as a developer for black-and-white film, marketed under the name Rodinal.

Is 2-aminophenol an acid or base?

2-Aminophenol is a strong basic compound (based on its pKa).

Is 2-aminophenol soluble in water?

2-Aminophenol is an organic compound with the formula C6H7NO….2-Aminophenol.

Names
Density	1.328 g/cm3
Melting point	174 °C (345 °F; 447 K)
Solubility in water	slightly soluble in cold water, soluble in hot water
Acidity (pKa)	4.78 (amino; 20 °C, H2O) 9.97 (phenol; 20 °C, H2O)

Is aminophenol a base?

Abstract. Aminophenols and their derivatives are of commercial importance, both in their own right and as intermediates in the photographic, pharmaceutical, and chemical dye industries. They are amphoteric and can behave either as weak acids or weak bases, but the basic character usually predominates.

How do you make para-aminophenol?

Para-Aminophenol can be produced by the reduction of p-nitrophenol using iron as a catalyst. P-nitrophenol is produced by the phenol nitrosation method which is followed by reduction and acid precipitation.

What is 2 Aminopyrimidine used for?

It is used to make pharmaceuticals and dyes.

What is para aminophenol derivatives?

The para- aminophenol derivatives include acetaminophen, and the indole acetic acid derivatives include indomethacin and etodolac. The heteroarylacetic acid derivatives are typified by diclofenac. Arylpropionic acids include ibuprofen and naproxen.

What are aminophenol derivatives?

What is para-aminophenol derivatives?

What is p-aminophenol soluble in?

Slightly soluble in toluene, diethyl ether, ethanol, cold water; soluble in acetonitrile, ethyl acetate, acetone, hot water; very soluble in dimethylsulfoxide.

Is 2 aminopyridine soluble in water?

Aminopyridine is a white or clear colored crystalline solid. It is soluble in water and alcohol. It is toxic by ingestion and by inhalation of the dust.

How is 2 aminopyridine formed?

It is one of three isomeric aminopyridines. It is a colourless solid that is used in the production of the drugs piroxicam, sulfapyridine, tenoxicam, and tripelennamine. It is produced by the reaction of sodium amide with pyridine, the Chichibabin reaction.

Is p-aminophenol acetaminophen?

Abstract. p-Aminophenol (PAP) is a widely used industrial chemical and a metabolite of analgesics, such as acetaminophen (APAP).

How do you make p-aminophenol?

Conventionally p-aminophenol was manufactured using iron-acid reduction of p-nitrobenzene. Reduction using iron-acid is a multi-step process. The modern method is the catalytic dehydrogenation of nitrobenzene to p-aminophenol (PAP) using a noble metal catalyst in the presence of an acidic medium.

Is 4 aminophenol an acid or base?

4-Aminophenol, also known as 4-aminobenzenol or 4-hydroxyaniline, belongs to the class of organic compounds known as aniline and substituted anilines….3D Structure for HMDB0001169 (4-Aminophenol)

Property	Value	Source
logS	0.04	ALOGPS
pKa (Strongest Acidic)	10.4	ChemAxon
pKa (Strongest Basic)	5.43	ChemAxon

Is p-aminophenol a drug?

p-Aminophenol (PAP) is a widely used industrial chemical and a metabolite of analgesics, such as acetaminophen (APAP). It was found recently that PAP, a known nephrotoxicant, could cause acute hepatotoxicity in mice but not in rats. The mechanism of hepatotoxicity is not known.

What is aminopyridine used for?

Introduction. 4-Aminopyridine (4-AP) is a nonselective blocker of several voltage-sensitive potassium channels. It is used clinically in the symptomatic treatment of demyelinating diseases such as spinal cord injury or multiple sclerosis. It is also used as a bird poison.

How do you make paracetamol from p-aminophenol?

Paracetamol is prepared from p- aminophenol by acetylating it with acetic anhydride in the presence of 3-4 drops of concentrated sulphuric acid as catalyst.

Is p-aminophenol toxic?

p-Aminophenol was also toxic to renal epithelial cells. Coincubation of p-aminophenol with tetraethylammonium bromide, a competitive inhibitor of the organic cation transporter, and with SKF-525A, an inhibitor of cytochrome P450, protected cells from p-aminophenol-induced toxicity.

What is 2-aminophenyl hydrogen sulfate?

2-aminophenyl hydrogen sulfate is an aryl sulfate that is 2-aminophenol in which the phenolic hydrogen has been replaced by a sulfo group. It is an aryl sulfate and a substituted aniline.

What is the pKa of 2-aminophenol?

Measured pKa values are 4.72 and 9.71 (5), for the amine and hydroxy functional groups, respectively (6); 2-aminophenol is amphoteric and behaves either as a weak acid or weak base; the basic character usually predominates (5). At pH 8.4, 25.5% of added 2-aminophenol is sorbed by an organoclay (7).

How to synthesize 2-aminophenol?

Reflecting its slight hydrophilic character, white powder is moderately soluble in alcohols and can be recrystallized from hot water. 2-Aminophenol (and its isomer, 4-aminophenol) is industrially synthesized by reducing the corresponding nitrophenol by hydrogen in the presence of various catalysts. The nitrophenols can also be reduced with iron.

What is the chemical formula for 2-aminophenol?

2-aminophenol is the aminophenol which has the single amino substituent located ortho to the phenolic -OH group. It has a role as a bacterial metabolite. O-aminophenol appears as off-white crystals or beige powder. (NTP, 1992) 2-aminophenol Computed by LexiChem 2.6.6 (PubChem release 2019.06.18) InChI=1S/C6H7NO/c7-5-3-1-2-4-6 (5)8/h1-4,8H,7H2