What does a person with Noonan syndrome look like?

Teeth may be crooked, the inside roof of the mouth (palate) may be highly arched and the lower jaw may be small. Facial features may appear coarse, but appear sharper with age. The face may appear droopy and expressionless. Head may appear large with a prominent forehead and a low hairline on the back of the head.

Can you have mild Noonan syndrome?

Noonan syndrome can range from being very mild to severe and life-threatening. In many cases, the problems associated with the condition can be successfully treated at a young age or become less prominent over time.

Is Noonan syndrome a disability?

The majority of children who are diagnosed with Noonan syndrome have average intelligence, although a small percentage have special educational needs, and some experience intellectual disability.

How long is the average lifespan of a person with Noonan syndrome?

It is one of the most common non-chromosomal disorders in children with congenital heart disease, with an estimated prevalence worldwide of 1 in 1000-2500. The average age at diagnosis is nine years, and life expectancy is likely normal if serious cardiac defects are absent.

Is Noonan syndrome like autism?

Few reports have described the psychiatric co-morbidity of Noonan syndrome. While mental retardation is a common feature of Noonan syndrome, the diagnosis of autism using operational criteria has not been reported. In this paper, the authors describe the association of Noonan syndrome with autism.

What part of the body does Noonan syndrome affect?

Noonan syndrome is a condition that some babies are born with. It causes changes in the face and chest, usually includes heart problems, and slightly raises a child’s risk of blood cancer (leukemia). Noonan syndrome is a pretty common condition, affecting 1 in 1,000–2,500 babies.

Does Noonan syndrome affect behavior?

behavioural problems – some children with Noonan syndrome may be fussy eaters, behave immaturely compared to children of a similar age, have problems with attention and have difficulty recognising or describing their or other people’s emotions.

Does Noonan syndrome have mental retardation?

The cardinal features of Noonan syndrome include unusual facies (ie, hypertelorism, down-slanting eyes, webbed neck), congenital heart disease, short stature, and chest deformity. Approximately 25% of individuals with Noonan syndrome have mental retardation.

Does Noonan syndrome affect males or females?

Noonan syndrome affects both males and females, and there is a normal chromosomal makeup (karyotype). Only females are affected by Turner syndrome, which is characterized by abnormalities affecting the X chromosome.

Is Noonan’s hereditary?

Noonan syndrome is most often an autosomal dominant genetic disorder caused by abnormalities (mutations) in several different genes, the main ones being: PTPN11, KRAS, SOS1 RIT1 and RAF1.

What is the life span for Noonan syndrome?

What is the life span for noonan syndrome??? Noonan: Life expectancy is reduced in Noonan syndrome by 10 years, mostly related to complications of Noonan syndrome related to their heart and bleeding tend… Read More Is reduced 10 yrs.: It depends on the severity of complications of individual living with Noonan syndrome.

What is the prognosis for Noonan syndrome?

Noonan syndrome prognosis. Noonan syndrome can range from being very mild to severe and life-threatening. The majority of patients with Noonan syndrome lead normal lives. Prognosis is largely dependent on the type and severity of cardiac disease, which may occur in 50% to 80% of cases.

What are the causes of Noonan syndrome?

Lymphedema (a buildup of fluid that causes swollen hands or feet)

Is Noonan syndrome life threatening?

While Noonan syndrome is not life-threatening, if you have the condition you may experience associated illnesses, including heart disease, bleeding disorders, and some types of cancer at some point during your lifetime. Likewise, is Noonan syndrome curable? As Noonan syndrome stems from a genetic defect, there is no cure. Treatment aims to manage the associated symptoms and complications, so it varies for each individual.