What is the difference between Chrpe and nevus?

CHRPE (congenital hypertrophy of the RPE) is also a benign pigmented ocular lesion. They are often much larger and more heavily pigmented than nevi. Despite their appearance, however, they cause no vision loss and have almost no potential to turn cancerous.

Can Chrpe become malignant?

Although CHRPE is usually a benign nonprogressive lesion, it can give rise to a malignant tumor. Congenital hypertrophy of the retinal pigment epithelium should be observed periodically for development of a neoplasm.

What is a chirpy in the eye?

Congenital Hypertrophy of the Retinal Pigment Epithelium, referred to as CHRPE (“chirpy”), a form of freckling inside the eye has been associated with a hereditary condition known as Familial Adenomatous Polyposis (FAP) or Gardner’s Syndrome. 80% of patients with FAP have CHRPE.

Does Chrpe mean I have FAP?

Congenital hypertrophy of the retinal pigment epithelium (also called CHRPE) is an abnormality found in the retina of the eye that looks like a freckle and causes no symptoms for the patient. While CHRPE can be seen in one eye of individuals without FAP, but it is often present in both eyes in a FAP patient.

Is Chrpe a tumor?

Congenital hypertrophy of the retinal pigment epithelium (CHRPE) is a typically benign, asymptomatic, pigmented fundus lesion. It is a congenital hamartoma of the retinal pigment epithelium (RPE) and occurs in three variant forms: solitary (unifocal), grouped (multifocal) and atypical.

How common are Chrpe?

The prevelance of CHRPE in the normal population is between 1.2% to 4.4% [23] which increases its specificity for screening.

Should I worry about Chrpe?

The Dangers of CHRPE. While a CHRPE may grow slightly over time, it is not malignant. Thus, it does not pose a risk of spreading to other parts of your body. It rarely leads to any noticeable symptoms for your eyes; therefore, a CHRPE does not pose a risk to your vision.

Are you born with Chrpe?

It can be detected in an eye exam by your primary optometrist, ophthalmologist, or retina specialist. This is a congenital condition meaning you are born with it, but it may go undetected until later in adulthood. In the vast majority of cases, CHRPE is a benign finding that never causes a problem with vision or life.

How common is eye nevus?

Iris nevus Approximately 6 in 10 people have one. Research has associated increased sun exposure to formation of new iris nevi, but more studies need to be done. They’re always flat and don’t pose any risk. These are different from raised masses on the iris or iris melanoma.

How common are nevus in the eye?

Wills Eye Hospital, which sees a vere large number of cases, states, “Choroidal nevus is the most common intraocular tumor, occurring in about seven percent of adults.” Suffice it to say, approximately 1 in 10 people have these freckles. They are never present at birth, though.

Is nevus benign or malignant?

A benign (not cancer) growth on the skin that is formed by a cluster of melanocytes (cells that make a substance called melanin, which gives color to skin and eyes). A nevus is usually dark and may be raised from the skin. Also called mole.

What causes nevus in eye?

Often nevi (especially iris nevi) result from sun exposure, just like freckles do for some people. You may be at risk if you have a light complexion and light-colored eyes (blue or green). Babies might be born with conjunctival nevi, or this type might also form during childhood.

How do you get rid of an eye nevus?

Treatments. A benign choroidal nevus requires no treatment and there is no way to safely remove them. Since a choroidal nevus can turn into a choroidal melanoma, it is reasonable to have it periodically observed by your eye care professional.

What is the difference between naevus depigmentosus and nevus?

Often, smaller hypopigmented macules arise around the edges, resembling a splash of paint. Achromic naevus (American spelling nevus) is also called naevus depigmentosus and non- pigmented naevus.

What are the characteristics of a Nevi lesion?

Characteristics of Nevi. Histologically, nevi are benign neoplasms of the melanocytes that reside in the outer layers of the choroid. They typically appear as a flat, slate-grey lesion beneath the retina.

What are the distinguishable characteristics of choroidal nevus?

Yet, several distinguishable characteristics may be noted in both lesions. • Choroidal nevi are relatively common, and are documented in 5% to 10% of the American population. 1 They are flat, green or slate gray choroidal lesions that typically measure less than 3.0DD, yet the size and thickness of choroidal nevi vary widely.

What is the difference between lesions and CHRPE?

Lesions are usually detected on dilated indirect or contact lens examination of the fundus. Solitary CHRPE is typically a single, flat, round, hyperpigmented retinal lesion. Color may vary from light gray to brown to black, with smooth or scalloped margins.