What is the use of co Trimazole?

Co-trimoxazole is used to treat certain bacterial infections, such as pneumonia (a lung infection), bronchitis (infection of the tubes leading to the lungs), and infections of the urinary tract, ears, and intestines. It also is used to treat ‘travelers’ diarrhea.

What is Biseptol used for?

Biseptol (Sulfamethoxazole-trimethoprim), is a combination of sulfonamide and trimethoprim. The combination eliminates bacteria that cause many kinds of infections, including pneumonia and urinary tract and intestinal infections.

What is co-trimoxazole explain mechanism of action?

Mechanism : Co-trimoxazole, (i.e. trimethoprim and sulfamethoxazole) is a synthetic antibacterial combination product. Sulfamethoxazole inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA).

How does co-trimoxazole inhibit bacterial growth?

Mechanism of co-trimoxazole effects Bacteria are unable to take up folic acid from the infection host and, thus, are dependent on their own synthesis. Inhibition of the enzyme starves the bacteria of two bases (thymidine and uridine) which are necessary for DNA replication and transcription.

What is Novatrim suspension used for?

Nevirapine and zidovudine are both HIV medicines. They are only given to you baby for a short time – usually four weeks. Novatrim is an antibiotic that is also called cotrimoxazole This tablet contains two antibiotics. This is usually given to the baby afterwards and for a much longer time.

What is trisul used for?

TRISUL is used to treat infections of the urinary tract, upper and lower respiratory tract and bowel. TRISUL contains two active ingredients, sulfamethoxazole and trimethoprim. They belong to a group of medicines known as antibiotics and work by stopping the growth of bacteria that is causing your infection.

What enzyme does sulfamethoxazole inhibit?

Sulfamethoxazole competitively inhibits dihydropteroate synthase, the enzyme responsible for bacterial conversion of PABA to dihydrofolic acid. Inhibition of this pathway prevents the synthesis of tetrahydrofolate and, ultimately, the synthesis of bacterial purines and DNA, resulting in a bacteriostatic effect.

Is sulfa a sulfonamide?

Sulfa drugs, also called sulfonamides, include antibiotics as well as other types of drugs. Allergies happen most often with antibiotics. About 3 percent of people have some type of reaction to them.

What class of antibiotic is cotrimoxazole?

Co-trimoxazole belongs to a class of drugs called sulfur or sulfonamides drugs. It contains two antibiotics, trimethoprim and sulfamethoxazole, which work together in the treatment of infections caused by bacteria. It is only available with a doctor’s prescription.

Why cotrimoxazole is preferred over sulfonamide?

A large number of sulfonamides were produced and used extensively in the subsequent years, but because of rapid emergence of bacterial resistance and the availability of many safer and more effective antibiotics, their current utility is limited, except in combination with trimethoprim (as cotrimoxazole) or …

What is Nova trim?

Through use, paraglider lines shrink or stretch. Generally, A and B lines stretch, whereas C lines shrink. As a result the wing flies slower and the handling is less agile. All lines are affected in this way – regardless of material or manufacturer.

What is Volutrip?

WHAT VOLUTRIP IS USED FOR VOLUTRIP is a triple combination therapy used to treat human immunodeficiency virus (HIV) infection in adults aged 18 years and older.

How does chloramphenicol work?

Chloramphenicol stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis. Chloramphenicol is lipid-soluble, allowing it to diffuse through the bacterial cell membrane.

Who needs cotrimoxazole?

Co-trimoxazole prophylaxis is recommended for adults (including pregnant women) with severe or advanced HIV clinical disease (WHO stage 3 or 4) and/or with a CD4 count of ≤350 cells/mm3.

What is the function of sulfamethoxazole?

Sulfamethoxazole (SMZ or SMX) is an antibiotic. It is used for bacterial infections such as urinary tract infections, bronchitis, and prostatitis and is effective against both gram negative and positive bacteria such as Listeria monocytogenes and E. coli.

What is the other name for cotrimoxazole?

Septrin is a brand name for a combination of antibiotics called cotrimoxazole. The same medication is available from other manufacturers with many different brand names, including Bactrim. Cotrimoxazole has two components: sulfamethoxazole and trimethoprim.

Is co-trimoxazole a penicillin?

Co-trimoxazole is a combination antibiotic. It can be taken by people who are allergic to penicillin, but it is not suitable for people who are allergic to sulfonamides. Space out your doses evenly throughout the day, and remember to finish the course of treatment.

What are bagels and lox?

A bagel with lox traditionally consists of an open-faced bagel topped with a generous smear of plain cream cheese, thinly sliced red onions and capers and lox.

Can DNA polymerase be inserted in motifs A B and C?

Thereafter, many cases of DNA polymerases containing various pattern of inteins, inserted in motifs A, B, and C, were discovered (Perler, 2002). The fidelity of DNA synthesis in vitrois markedly affected by the reaction condition.

What is thermophilic DNA polymerase?

Thermophilic organisms utilize thermostable DNA polymerases, and therefore, thermophiles became more popular as genetic resources of DNA polymerases and other enzymes for industrial use. The heat stability of the enzymes is directly related to the temperature, at which the organism thrives.

Is resveratrol a DNA polymerase inhibitor?

On the basis of the structures of 1 and 2, resveratrol (3) was tested and found to be active as a DNA polymerase inhibitor in this bioassay. Neobavaisoflavone (4) was isolated as a DNA polymerase inhibitor, daidzein (5) as a DNA polymerase and topoisomerase II inhibitor, and bakuchicin (6) as a topoisomerase II inhibitor.

What is Thermotoga maritima DNA polymerase?

Thermotoga maritimaDNA polymerase was the first commercial product (ULTIMA DNA polymerase) from the hyperthermophilic bacteria. This enzyme has an associated 3′–5′exonuclease activity and thus is expected to perform PCR more accurately with its proofreading activity.