What is the function of Zoladex 10.8 mg?
What is the function of Zoladex 10.8 mg?
Zoladex 10.8 (goserelin acetate implant) is a man-made form of a hormone used in men to treat symptoms of prostate cancer, and in women to treat breast cancer or endometriosis.
How long does Zoladex 10.8 last?
Zoladex 10.8 is a special preparation of goserelin acetate which is designed to work in the body for 12 to 13 weeks after each injection. Most people will need one injection for each 12 to 13 weeks of treatment.
What is the drug Zoladex used for?
Goserelin is a type of hormone therapy. It is also known as Zoladex. This page is about goserelin for breast cancer in women who haven’t gone through the menopause. Goserelin is also a treatment for prostate cancer and is sometimes used to treat men with breast cancer.
What is the mechanism of action of Zoladex?
On chronic administration Zoladex results in inhibition of pituitary LH secretion leading to a fall in serum testosterone concentrations in males and serum oestradiol concentrations in females. This effect is reversible on discontinuation of therapy.
What are the effects of Zoladex?
Hot flashes (flushing), dizziness, headache, increased sweating, decreased sexual interest/ability, trouble sleeping, nausea, change in breast size, vaginal dryness, or hair loss may occur. Pain, bruising, bleeding, redness, or swelling at the injection site may also occur.
Is Zoladex safe?
Injection site injury (including damage to blood vessels in the abdomen) has been reported following injection of Zoladex. In very rare cases this has caused severe bleeding. Contact your doctor immediately if you experience any of the following symptoms: Abdominal pain.
How do you inject Zoladex 10.8 mg?
Zoladex step-by-step administration guide
- Clean the injection-site area. Clean an area of the anterior abdominal wall (below the navel) for injection using an alcohol swab.
- Inspect the syringe. Inspect the foil pouch and syringe for damage.
- Pinch the skin.
- Insert the needle.
- Depress the plunger.
- Withdraw the needle.
How long can I take Zoladex for?
To treat uterine fibroids, you should only have Zoladex for up to three months. To treat endometriosis, you should only have Zoladex for up to six months. To make the lining of your uterus thinner before an operation on your womb, you should only have Zoladex for one or two months (four or eight weeks).
When should Zoladex be given?
The implant is given as an injection under the skin on your stomach by your doctor or nurse. Zoladex should be given every month (four weeks). Always remind your doctor or nurse to set up an appointment for your next injection.
What are side effects of Zoladex?
What kind of drug is Zoladex?
Zoladex contains the drug goserelin, which belongs to a class of medications called gonadotropin releasing hormone (GnRH) agonists. (A medication class is a group of drugs that work in a similar way.) Zoladex is a type of hormone therapy that works to lower levels of sex hormones such as testosterone and estrogen.
What happens after stopping Zoladex?
When you stop having the drug, your ovaries will usually start to produce oestrogen again. Most women will start their periods within three months to a year after finishing treatment. However, if you’re approaching the age of natural menopause when your treatment finishes, your ovaries may not start working again.
What are the long term side effects of Zoladex injection?
What are the serious side effects of Zoladex?
- injection site injuries*
- depression*
- high blood sugar level.
- raised level of calcium in your blood.
- long QT syndrome, a rare but serious heart rhythm problem.
- serious cardiovascular (heart and blood vessel) problems, such as stroke or heart attack.
Is Zoladex better than tamoxifen?
Compared to women who didn’t get either medicine, the risk of breast cancer coming back was 33% lower for women who got 2 years of Zoladex and 29% lower for women who got 2 years of tamoxifen.
Is Zoladex chemotherapy?
Zoladex – Chemotherapy Drugs – Chemocare.
What happens after first Zoladex injection?
After goserelin has been given, you may notice an area of redness or bruising at the injection site, but this should disappear within a few hours. Occasionally, bruising may be there for a few days. Some women notice a change in their breast size.
What happens when I stop Zoladex?
Is Zoladex a form of chemotherapy?
Is Zoladex chemo?
Does Zoladex affect sleep?
nausea, diarrhea, sleep problems (insomnia), acne, or.
What is Zoladex used for?
Zoladex is a GnRH agonist, which stands for gonadotropin-releasing hormone agonist. Zoladex blocks a hormone produced in the brain called GnRH that triggers the ovaries to make estrogen. 1 Blocking the ovaries from making estrogen is called ovarian suppression. It can slow the growth of HR+ breast cancer or help prevent it from coming back. 1-3
What is the ATC code for Zoladex?
ATC code: L02AE03. Zoladex (D-Ser (Bu t) 6 Azgly 10 LHRH) is a synthetic analogue of naturally occurring luteinising-hormone releasing hormone (LHRH). On chronic administration Zoladex LA results in inhibition of pituitary luteinising hormone secretion leading to a fall in serum testosterone concentrations in males.
When is Zoladex used as an alternative to castration?
• In the treatment of metastatic prostate cancer where Zoladex has demonstrated comparable survival benefits to surgical castrations (see section 5.1) • In the treatment of locally advanced prostate cancer, as an alternative to surgical castration where Zoladex has demonstrated comparable survival benefits to an anti-androgen (see section 5.1)
Is Zoladex La safe for the treatment of ureteric obstruction?
The use of Zoladex LA in patients at particular risk of developing ureteric obstruction or spinal cord compression should be considered carefully and the patients monitored closely during the first month of therapy.
