What is Mexazolam used for?

Mexazolam (also known as CS-386) is currently indicated for the management of anxiety with or without psychoneurotic conditions when the disorder is severe, disabling, or subjecting the individual to extreme distress [16].

What are the indications of benzodiazepines?

Indications for benzodiazepine administration include, but are not limited to, anxiety disorders, insomnia, acute status epilepticus, induction of amnesia, spastic disorders, seizure disorders, and agitation.

What contraindications are associated with benzodiazepines?

Contraindications. Because of their muscle relaxant action, benzodiazepines may cause respiratory depression in susceptible individuals. For that reason, they are contraindicated in people with myasthenia gravis, sleep apnea, bronchitis, and COPD.

What are the contraindications of diazepam?

Who should not take DIAZEPAM?

• low amount of albumin proteins in the blood.
• alcohol intoxication.
• drug abuse.
• depression.
• myasthenia gravis, a skeletal muscle disorder.
• wide-angle glaucoma.
• closed angle glaucoma.
• worsening of debilitating chronic lung disease called COPD.

Is Mexazolam a benzodiazepine?

Mexazolam (CS-386) is a benzodiazepine indicated for the treatment of anxiety with or without psychoneurotic conditions. Mexazolam’s structure is similar to that of other benzodiazepines such as oxazolam and cloxazolam.

Is Mexazolam a narcotic?

Mexazolam (marketed under the trade names Melex and Sedoxil) is a drug which is a benzodiazepine derivative. Mexazolam has been trialed for anxiety and was found to be effective in alleviating anxiety at one week follow-up….Mexazolam.

Clinical data
Trade names	Melex, Sedoxil

What are the most common side effects of benzodiazepines?

The most common side effects of benzodiazepines include:

• drowsiness.
• light-headedness.
• confusion.
• unsteadiness (especially in older people, who may fall and experience injuries)
• dizziness.
• slurred speech.
• muscle weakness.
• memory problems.

What are the risks of benzodiazepines?

Benzodiazepines increase the risk of addiction, withdrawal, cognitive decline, motor vehicle crashes, and hip fracture. The risk of overdose is particularly great when combined with sedative drugs such as opioids or alcohol.

What are the major side effects of benzodiazepines?

What is diazepam used to treat?

Diazepam: medicine for anxiety, muscle spasms and seizures – NHS.

Is Midazolam used for anxiety?

Midazolam injection is used to produce sleepiness or drowsiness and relieve anxiety before surgery or certain procedures.

What is the most serious risk associated with the use of benzodiazepine?

Which is the main action of benzodiazepines?

Benzodiazepines work by enhancing a very important neurotransmitter called GABA (gamma-aminobutyric acid) at the GABA A receptor. This results in the sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties for which the drugs are prescribed.

What are the benefits of benzodiazepines?

The beneficial effects of benzodiazepines include the reduction of anxiety, the induction and main- tenance of sleep, muscle relaxation, and the treat- ment and prevention of epileptic seizures.

Can benzodiazepines lower blood pressure?

It has been previously demonstrated that benzodiazepines can help reduce acute elevation of blood pressure in hypertensive patients.

What do you need to assess before prescribing a benzodiazepine?

Assess the patient’s response to the initial dose reduction in the first 1 to 4 weeks. Assess the patient’s underlying condition for which the drugs were originally prescribed; discuss alternative treatments as needed. Assess the patient for readiness/suitability to taper off benzodiazepines.

Does diazepam lower blood pressure?

Diazepam reduces both arterial blood pressure and muscle sympathetic nerve activity in human. Neurosci Lett.

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