Is Microglandular hyperplasia cancerous?

Microglandular hyperplasia is a benign condition without preneoplastic potential. It requires no therapy. However, this case fits the profile of uterine cancers misinterpreted as microglandular hyperplasias that was described by Young and Scully [1].

What does Microglandular mean?

Definition. Microglandular hyperplasia (MGH) is a localized nonneoplastic proliferation of endocervical glands in women of reproductive age. It is associated with oral contraceptive use, pregnancy, and progestins (Fig. 1). Microglandular Hyperplasia, Cytological Findings, Fig.

What is endocervical hyperplasia?

Lobular endocervical glandular hyperplasia (LEGH) is a rare lesion of the uterine cervix. It has been proposed that LEGH may represent a precursor lesion to a group of mucinous adenocarcinoma with gastric phenotype (GA) that is independent of high-risk human papillomavirus (H-HPV) infection.

What is Microglandular Adenosis?

Microglandular adenosis is a rare borderline neoplastic lesion of the breast composed of haphazardly located small, round tubules with a single cell layer interspersed within breast stroma and/or adipose tissue.

What is endocervical mucosa?

The mucous lining of the canal of the cervix uteri. It is composed of epithelium, basement membrane, lamina propria mucosae, and lamina muscularis… Expand.

What causes Microglandular hyperplasia?

Microglandular hyperplasia is a lesion of the uterine endocervical mucosa, often associated with a story of contraceptive drugs or pregnancy.

What is squamous metaplasia cervix?

Squamous metaplasia in the cervix refers to the physiological replacement of the everted columnar epithelium on the ectocervix by a newly formed squamous epithelium from the subcolumnar reserve cells. The region of the cervix where squamous metaplasia occurs is referred to as the transformation zone.

What is the cause of cervical polyps?

The exact cause of cervical polyps is not known. Possible causes include: congestion of blood vessels in your cervix. infection or chronic (long-term) inflammation of your cervix.

What is endocervical adenocarcinoma?

Adenocarcinoma is a cancer that starts in the gland cells that produce mucus. The cervix has glandular cells scattered along the inside of the passage that runs from the cervix to the womb (the endocervical canal). Adenocarcinoma is less common than squamous cell cancer, but has become more common in recent years.

What is Microglandular hyperplasia?

Microglandular hyperplasia is a lesion of the uterine endocervical mucosa, often associated with a story of contraceptive drugs or pregnancy. It was frequently confused with adenocarcinoma or premalignant glandular changes until its benign nature was recognized.

What is ductal hyperplasia?

In usual ductal hyperplasia, there is an overgrowth of cells lining the ducts in the breast, but the cells look very close to normal. In atypical hyperplasia (or hyperplasia with atypia), the cells look more distorted and abnormal.

Is hyperplasia cancerous?

An increase in the number of cells in an organ or tissue. These cells appear normal under a microscope. They are not cancer, but may become cancer.

What are the symptoms of hyperplasia?

Symptoms of endometrial hyperplasia

• Menstrual bleeding that is heavier or longer lasting than usual.
• Menstrual cycles (amount of time between periods) that are shorter than 21 days.
• Menstrual bleeding between menstrual periods.
• Not having a period (pre-menopause).
• Post-menopause uterine bleeding.

What does it mean when endocervical cells are present?

The phrase “endocervical cells present” simply means that your doctor sampled cells from the inside of your cervix during the Pap smear. The phrase “squamous metaplastic cells present” means that the pathologist who examined your Pap smear found cells that were growing and repairing themselves regularly.

How are cervical polyps diagnosed?

Your health care provider will perform your pelvic exam. Some smooth, red or purple fingerlike growths will be seen on the cervix. Most often, the provider will remove the polyp with a gentle tug and send it for testing. Most of the time, the biopsy will show cells that are consistent with a benign polyp.

What does endocervix mean?

(EN-doh-SER-vix) The inner part of the cervix that forms a canal that connects the vagina to the uterus. The endocervix is lined with glandular cells that make mucus.

How do you treat endocervical polyps?

How are cervical polyps treated?

1. To remove it, the polyp is gently twisted using an instrument called polyp forceps until the polyp tissue comes away from your cervix and is removed.
2. After removal of your polyp, there may be light bleeding and slight cramping for a few days.

How are endocervical polyps removed?

The removal of endometrial or cervical polyps is a relatively simple procedure. Some cervical polyps are completely seen outside the cervix and can be removed in a doctor’s office or surgery with an instrument called a polyp forceps. Endometrial polyps and deeply positioned cervical polyps require a hysteroscopy.

How aggressive is adenocarcinoma of the cervix?

Small cell carcinomas of the cervix tend to be highly aggressive and have low survival rates. They’ve often spread to lymph nodes and other parts of the body by the time of diagnosis. Treatment options often mimic those of small cell lung cancer, and include a combination of surgery, chemotherapy and radiotherapy.

What is Microglandular hyperplasia of cervix?

(Definition/Background Information) Microglandular Hyperplasia (MGH) of Uterine Cervix is a benign condition that occurs due to an abnormal increase of glands (endocervical glands) within the cervix It is mostly diagnosed in young adult women or during pregnancy. Microglandular Hyperplasia of Cervix is believed to form due to hormonal factors

What is Microglandular adenocarcinoma of the endometrium?

“Microglandular adenocarcinoma of the endometrium: a form of mucinous adenocarcinoma that may be confused with microglandular hyperplasia of the cervix”. Int J Gynecol Pathol. 16 (1): 52–9. doi: 10.1097/00004347-199701000-00009.

What is an endocervical curette?

Endocervical curettage (endocervical scraping): The curette is an instrument that can be used to scrape out tissue. Using a curette, cells are scraped out from the endocervix (the inner part of the cervix, close to the uterus/womb) and examined under a microscope.

What is MGH of the uterine cervix?

(Definition/Background Information) Microglandular Hyperplasia (MGH) of Uterine Cervix is a benign condition that occurs due to an abnormal increase of glands (endocervical glands) within the cervix It is mostly diagnosed in young adult women or during pregnancy.