Is TIMENTIN still available?

Septicemia • Lower respiratory infections • Bone and joint infections • Skin and skin structure infections • Urinary tract infections • Gynecologic infections • Intra-abdominal infections We wish to alert you that GlaxoSmithKline has ceased manufacturing TIMENTIN® for the US.

What type of drug is TIMENTIN?

TIMENTIN is a sterile injectable antibacterial combination consisting of the semisynthetic antibiotic ticarcillin disodium and the β-lactamase inhibitor clavulanate potassium (the potassium salt of clavulanic acid) for intravenous administration.

What is TIMENTIN used for?

Timentin Injection is a prescription medicine used to treat the symptoms of many different bacterial infections such as urinary tract infection, bone and joint infections, severe vaginal infections, and skin infections. Timentin Injection may be used alone or with other medications.

Is TIMENTIN an antibiotic?

Timentin (ticarcillin disodium and clavulanate potassium) is a combination of a penicillin antibiotic and a form of clavulanic acid, similar to penicillin, used to treat many different infections caused by bacteria, such as urinary tract infections, bone and joint infections, severe vaginal infections, stomach …

Is ticarcillin the same as timentin?

Trade names and preparations. Ticarcillin: Ticar was formerly marketed by Beecham, then SmithKline Beecham until 1999, when it merged with Glaxo to form GlaxoSmithKline; it is no longer available in the UK. US distribution ceased in 2004. Ticar was replaced by Timentin.

Is ticarcillin still used?

Ticarcillin was withdrawn from the market in the United States in 2004. Previously it was available in parenteral forms generically and under the name Ticar and is usually given in doses of 200 to 300 mg/kg per day in divided doses intravenously every 4 to 6 hours.

Is timentin broad spectrum?

Ticarcillin-clavulanate (Timentin) has a broad spectrum of activity, including gram-negative cocci other than enterococci and methicillin-resistant staphylococci; Enterobacteriaceae, including drug-resistant strains; P. aeruginosa; and gram-positive and gram-negative anaerobes.

What is another name for Piperacillin Tazobactam?

Zosyn (piperacillin / tazobactam) is a combination antibiotic medication used to treat a wide variety of bacterial infections.

Does timentin cover Pseudomonas?

Timentin and Zosyn have no significant activity against Pseudomonas beyond that of ticarcillin or piperacillin because their β-lactamase inhibitors do not effectively inhibit the β-lactamases of Pseudomonas.

Why is clavulanic acid is added to penicillin?

Introduction. Clavulanic acid is used with beta-lactamase sensitive penicillins to protect them against the hydrolysis of their beta-lactam ring and so rendering them effective against beta-lactamase producing bacteria.

What is the generic name for timentin?

GENERIC NAME: TICARCILLIN/CLAVULANATE POTASSIUM – INJECTION (tie-kar-SILL-in/KLAV-you-la-nate poh-tass-ee-um)

Is ticarcillin a penicillin?

Ticarcillin (tye” kar sil’ in) is a fourth generation, extended-spectrum penicillin antibiotic which was previously used for moderate-to-severe infections caused by susceptible gram positive and gram negative agents. The extended spectrum of ticarcillin made it an appropriate agent in therapy of Pseudomonas aeruginosa.

Why is Clavulanic acid is added to penicillin?

What is Ticarcillin used for?

Ticarcillin is an extended-spectrum carboxypenicillin antibiotic and is used to treat moderate-to-severe infections due to susceptible organisms.

Is piperacillin and tazobactam safe?

In all trials, piperacillin/tazobactam was found to be safe and well tolerated. One death was deemed possibly drug-related. Thirty-eight patients were withdrawn from the trials because of adverse experiences, most often diarrhoea and allergic skin reactions.

Is Timentin broad-spectrum?

Is ticarcillin the same as Timentin?

What is the brand name for amoxicillin and clavulanic acid?

Amoxicillin/clavulanic acid

Combination of
Amoxicillin	Penicillin antibiotic
Clavulanic acid	Beta-lactamase inhibitor
Clinical data
Trade names	Augmentin, Clavulin, Amoclan, others

Can timentin be taken in combination with other medications?

When TIMENTIN is given in combination with another antimicrobial, such as an aminoglycoside, each drug should be given separately in accordance with the recommended dosage and routes of administration for each drug [see Drug Interactions (7.1)].

How do you administer timentin?

TIMENTIN should be administered by intravenous infusion over a 30-minute period. Directions for Reconstitution and Further Dilution: 3.1 ‑ gram Glass Vials: The 3.1‑gram vial should be reconstituted by adding approximately 13 mL of Sterile Water for Injection, USP, or Sodium Chloride Injection, USP, and shaking well.

How long does it take for timentin to absorb?

TIMENTIN is an antibacterial drug [see Clinical Pharmacology (12.4)]. Absorption: After an intravenous infusion (30 minutes) of 3.1 grams of TIMENTIN, peak serum concentrations of both ticarcillin and clavulanic acid were attained immediately after completion of the infusion.