What medications should not be taken with warfarin?

Common drugs that can interact with warfarin include:

• Aspirin or aspirin-containing products.
• Acetaminophen (Tylenol, others) or acetaminophen-containing products.
• Antacids or laxatives.
• Many antibiotics.
• Antifungal medications, such as fluconazole (Diflucan)
• Cold or allergy medicines.

Which statin does not interact with warfarin?

Atorvastatin does not appear to interact with warfarin and should be considered the preferred statin for patients receiving warfarin therapy. All statins except pravastatin could interact with warfarin through protein-binding interactions or inhibition of warfarin metabolism.

Does simvastatin interact with warfarin?

The interaction mechanism between simvastatin and warfarin is not known but is possibly associated with reduced elimination of warfarin. Use of the Naranjo probability scale showed that the likelihood of warfarin-induced INR increase following the switch to simvastatin was probable.

What is lovastatin 40 mg used for?

Lovastatin is used together with a proper diet to lower cholesterol and triglyceride (fat) levels in the blood. This medicine may also help prevent medical problems (eg, chest pain, heart attack, stroke) caused by fat clogging the blood vessels.

Is there an interaction between warfarin and fluvastatin?

The literature supports a drug interaction between warfarin and fluvastatin due to the strong affinity of fluvastatin for the cytochrome P450 enzyme 2D6. This interaction has not been seen with atorvastatin.

Does initiation of simvastatin increase INR among warfarin users?

Initiation of atorvastatin and rosuvastatin lead to INR increases of 0.27 (95%CI 0.12-0.42) and 0.30 (95%CI -0.09-0.69). In conclusion, initiation of simvastatin, atorvastatin or rosuvastatin among warfarin users led to a minor increase in INR. The magnitude of this change is for most patients likely of limited clinical relevance.

Can warfarin and statin drugs be co-administered to patients with heart disease?

4 Development Center for Biotechnology, Taipei 221, Taiwan. The anticoagulant drug warfarin and the lipid-lowering statin drugs are commonly co-administered to patients with cardiovascular diseases.

Does atorvastatin interact with warfarin?

This interaction has not been seen with atorvastatin. Lovastatin also reportedly has caused increases in INR when coadministered with warfarin. It is unclear whether simvastatin interacts with warfarin, but it may increase INRs slightly or increase serum simvastatin levels.